Incidents of serious parasitic disease on the rise in Alberta

The province is now the North American hotspot for a rare, potentially fatal disease

Incidents of serious parasitic disease on the rise in AlbertaA rare parasitic infection imported from Europe continues to take root in Alberta. The province is now the North American hotspot for human alveolar echinococcosis (AE), which takes the form of a growth in the liver, causing serious and potentially deadly health complications. A recently published review of known AE cases in Alberta found 17 instances…

Next-generation genetic sequencing to detect pancreatic and biliary cancer

Nearly $1M awarded to seven new projects from U of A researchers focusing on cancer, pulmonary, diabetes and neurology research

Next-generation genetic sequencing to detect pancreatic and biliary cancerSeven new University of Alberta research projects focusing on cancer, pulmonary disease, diabetes and neurology are the latest recipients of funding from the 2020 Kaye Competition. The annual competition supports individuals and collaborative, interdisciplinary and multidisciplinary teams in the pursuit of research, innovation and quality-improvement programs and projects that seek to establish new approaches to patient…

Hearing loss caused by common childhood cancer drug targeted

Research may eliminate the toxic side-effect of cispaltin in childhood cancer survivors

Hearing loss caused by common childhood cancer drug targetedUniversity of Alberta scientists have identified a receptor in cells that could be key to preventing permanent hearing loss in childhood cancer survivors being treated with the drug cisplatin. The researchers believe that, by inhibiting the receptor, they may be able to eliminate toxic side-effects from the drug that cause the hearing loss. Cisplatin is…

Unique cardiac rehabilitation program gives cancer patients hope

Helps cancer patients who also face heart damage due to their treatment

Unique cardiac rehabilitation program gives cancer patients hopeAsk Paul Guenard how he’s doing, and he’ll tell you, “Not bad for a guy who’s supposed to be dead!” While he laughs as he says it, Guenard did indeed face death six years ago when he underwent a stem cell transplant to treat mantle cell lymphoma. Afterwards, he said, he felt so weak he…

Marker may predict response to cancer immunotherapy

Abundance of protein galectin-9 in cancer patients is associated with poor response to immunotherapy

Marker may predict response to cancer immunotherapyUniversity of Alberta researchers have uncovered a link between the expression of the protein galectin-9 (gal-9) and whether a cancer patient will benefit from immunotherapy. The discovery could help inform physicians about which patients will likely respond to immunotherapy and lead to better treatment options. Immunotherapy or biological therapy is the treatment of disease by…

3-D bioprinting successfully used to create nose cartilage

Searching for a better solution to a clinical problem facing many patients with skin cancer

A team of University of Alberta researchers has discovered a way to use 3-D bioprinting technology to create custom-shaped cartilage for use in surgical procedures. The work aims to make it easier for surgeons to safely restore the features of skin cancer patients living with nasal cartilage defects after surgery. The researchers used a specially…

Nanomedicine used to provide better outcomes during chemotherapy

Nanomedicine used to provide better outcomes during chemotherapyA University of Alberta researcher is using nanotechnology to improve the effectiveness of chemotherapy treatments for cancer patients and reduce their side effects. Afsaneh Lavasanifar is a professor in the University of Alberta’s Faculty of Pharmacy & Pharmaceutical Sciences and an adjunct professor in the Department of Chemical and Medical Engineering. Her lab develops precision health solutions through nanomedicine,…

Innovative cancer therapy uses immune system to attack tumours

Re-engineers your immune system to target and attack cancer growing in your body

Innovative cancer therapy uses immune system to attack tumoursImagine if you could re-engineer your immune system to target and attack cancer growing in your body. A new clinical trial led by a clinician researcher at the University of Alberta is doing just that. Michael Chu, an assistant professor of oncology in the Faculty of Medicine & Dentistry, is leading a project to manufacture and…

Muscle wasting syndrome cause of many cancer-related deaths

Project delves into how one growth hormone contributes to the problem and whether drugs can stop it

Muscle wasting syndrome cause of many cancer-related deathsResearchers are looking for ways to prevent or slow cachexia, a muscle-wasting syndrome thought to cause up to a third of the 80,000 deaths related to cancer every year in Canada. By understanding the role of activin A, a growth factor that contributes to muscle wasting, the team hopes their lab research will eventually help…

Research may help to accurately diagnose prostate cancer severity

Could predict which men are at risk of developing an aggressive form of the disease

Research may help to accurately diagnose prostate cancer severityScientists at the University of Alberta are part of a new research project to develop innovative precision diagnostics that could predict which men with prostate cancer are at risk of developing an aggressive form of the disease. The researchers will use germline sequencing (sequencing of the genes a person is born with) to determine which…

Safer source of islet cells targeted for people with Type 1 diabetes

U of A researchers are harnessing AI to analyze patients’ own cells to create islet cells for transplant

Safer source of islet cells targeted for people with Type 1 diabetesUniversity of Alberta researchers are harnessing the power of artificial intelligence to find a safer, more personalized source of islet cells to treat Type 1 diabetes. The research project, a collaboration between the departments of surgery and computing science, aims to use AI to analyze images to speed up the process and reduce the need for human decision-making…

Alberta not-for-profit runs cancer clinical trials around the world

Building on game-changing breast cancer trials, TRIO now testing drugs for breast, lung, ovarian, liver and gastrointestinal cancer

Alberta not-for-profit runs cancer clinical trials around the worldA not-for-profit research group with University of Alberta roots is quietly taking its place in the major leagues of global cancer drug testing. When promising new cancer treatments are ready for trial in humans, researchers from around the world turn to Edmonton-based TRIO (Translational Research in Oncology) to run their clinical trials. “It may seem like…

Ultrasound has potential for treating pain after chemotherapy

There may soon be a new option available to people experiencing sensory pain after chemotherapy

Ultrasound has potential for treating pain after chemotherapyTherapeutic ultrasound was a tool in Janice Yurick’s treatment arsenal for 15 years. Yurick, a now-retired physical therapist and former manager of supportive care services at the Cross Cancer Institute in Edmonton, Alberta had more than two decades of experience in oncology rehabilitation. She used the technology with patients and saw results, despite no actual…

Grads strive to improve care for LGBTQ2SPIA+ cancer patients

National survey identifies potential issues and areas for improvement among radiation therapy professionals

Grads strive to improve care for LGBTQ2SPIA+ cancer patientsA new study led by a group of recently graduated radiation therapy students at the University of Alberta shows that many in the profession feel more training is needed to properly care for cancer patients in the lesbian, gay, bisexual, trans, queer, two-spirit, pansexual, intersex, asexual, plus (LGBTQ2SPIA+) community. The team – Samantha Chan, Samie…

Pushing boundaries so women don’t have to ‘suffer in silence’

In honour of International Women’s Day, we celebrate three research-focused clinicians who are improving women’s health

Pushing boundaries so women don’t have to ‘suffer in silence’As the world marks International Women’s Day, we celebrate the scientists who are working to improve women’s health. More than 140 researchers are working on women, children’s and perinatal medicine through the Women and Children's Health Research Institute (WCHRI) at the University of Alberta, supported by the Alberta Women’s Health Foundation and the Stollery Children’s Foundation.…
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